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Table 7 Comparison of nomogram with AJCC staging system

From: Nomograms to predict survival after colorectal cancer resection without preoperative therapy

  Nomogram score 7th AJCC stage 6th AJCC stage P
Training cohort, CSS
 AIC 172262 174703 174949 /
 Log-likelihood −86130 −87344 −87468 All <0.0001
 C-index (95 % CI) 0.816 (0.810–0.822) 0.777 (0.771–0.783) 0.774 (0.768–0.780) All <0.0001
Training cohort, OS
 AIC 250348 255973 256182 /
 Log-likelihood −125173 −127979 −128085 All <0.0001
 C-index (95 % CI) 0.777 (0.772–0.782) 0.698 (0.693–0.0.703) 0.696 (0.691–0.701) All <0.0001
Validation cohort, CSS
 AIC 14983 15261 15272 /
 Log-likelihooda −7490 −7623 −7630 All <0.0001
 C-indexb (95 % CI) 0.809 (0.791–0.827) 0.770 (0.752–0.788) 0.768 (0.750–0.786) All <0.0001
Validation cohort, OS
 AIC 21611 22235 22244 /
 Log-likelihoodc −10805 −11110 −11116 All <0.0001
 C-indexd (95 % CI) 0.773 (0.757–0.789) 0.699 (0.683–0.715) 0.697 (0.681–0.713) All <0.0001
Test cohort, CSS
 AIC 102103 104057 105039 /
 Log-likelihood −51050 −52021 −52519 All <0.0001
 C-index (95 % CI) 0.838 (0.830–0.846) 0.794 (0.786–0.802) 0.786 (0.778–0.794) All <0.0001
Test cohort, OS
 AIC 141606 145343 146456 /
 Log-likelihood −70802 −72664 −73227 All <0.0001
 C-index (95 % CI) 0.802 (0.796–0.808) 0.723 (0.717–0.729) 0.715 (0.709–0.721) All <0.0001
  1. AJCC American joint committee on cancer, AIC akaike information criterion, C-index concordance index, 95 % CI 95 % confident interval
  2. aThe P value comparing 6th and 7th AJCC stage was 0.0003
  3. bThe P value comparing 6th and 7th AJCC stage was 0.5187
  4. cThe P value comparing 6th and 7th AJCC stage was 0.0006
  5. dThe P value comparing 6th and 7th AJCC stage was 0.3709