Skip to main content
Fig. 1 | BMC Cancer

Fig. 1

From: PNA clamping-assisted fluorescence melting curve analysis for detecting EGFR and KRAS mutations in the circulating tumor DNA of patients with advanced non-small cell lung cancer

Fig. 1

Schematic representation of EGFR and KRAS mutation detection using PANAMutyperTM: EGFR (a) and KRAS (b). Sensitivity of the EGFR L858R and E19del (c) and KRAS G12V and G12R (d) mutants according to their cellularity by diluting to 100, 10, 1, 0.1, 0.01, 0 % with respect to the wild cell line DNA and mutant cell line DNA. The data presented here are representative obtained from sensitivity test conducted more than 50 times. MT, mutant type

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us