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Fig. 2 | BMC Cancer

Fig. 2

From: MPO density in primary cancer biopsies of ovarian carcinoma enhances the indicative value of IL-17 for chemosensitivity

Fig. 2

a Kaplan Meier survival curve of recurrence-free survival according to MPO and IL-17 density in primary cancer biopsies. Impact of MPO+ and IL-17+ tumor infiltrating immune cells on recurrence-free survival in patients with high grade ovarian carcinoma. Kaplan-Meier recurrence-free survival curves were split according to MPO+ and IL-17+ cell density in patients bearing high grade ovarian carcinoma as indicated. Cut-off values established by regression tree analysis were 22 cells/punch for MPO and 1 cell/punch for IL-17 cell infiltration. Cumulative effects of tumor infiltration by MPO+ and IL-17+ cells were explored. Blue line indicates to tumors with low MPO+ and low IL-17+ cell infiltration. Green line refers to tumors with high IL-17+ cell infiltration. Red line refers to tumors with high MPO+ cell infiltration and yellow line refers to tumors with high MPO+ and high IL-17+ cell infiltration. b Kaplan Meier survival curve of overall survival according to MPO and IL-17 density in primary cancer biopsies. Impact of MPO+ and IL-17+ tumor infiltrating immune cells on overall survival in patients with high grade ovarian carcinoma. Kaplan-Meier overall survival curves were split according to MPO+ and IL-17+ cell density in patients bearing high grade ovarian carcinoma as indicated. Cut-off values established by regression tree analysis were 22 cells/punch for MPO and 1 cell/punch for IL-17 cell infiltration. Cumulative effects of tumor infiltration by MPO+ and IL-17+ cells were explored. Blue line indicates to tumors with low MPO+ and low IL-17+ cell infiltration. Green line refers to tumors with high IL-17+ cell infiltration. Red line refers to tumors with high MPO+ cell infiltration and yellow line refers to tumors with high MPO+ and high IL-17+ cell infiltration

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