BRCA1-associated protein 1 deficiency in lung adenocarcinoma predicts poor outcome and increased tumor invasion

BMC Cancer

Table 3 Correlation between BAP1 expression and clinicopathologic parameters of lung adenocarcinoma

Clinicopathological features		n	%	BAP1 Expression		P value
Clinicopathological features		n	%	Low	High	P value
All cases		112	100	80	32
Sex	Male	59	52.68	45	14	0.231
Sex	Female	53	47.32	35	18	0.231
Age (years) (Average 57.6)	<60	66	58.93	50	16	0.224
Age (years) (Average 57.6)	≥60	46	41.07	30	16	0.224
Gross Type	Central	82	73.21	59	23	0.840
Gross Type	Peripheral	30	26.79	21	9	0.840
Diameter of Tumor (cm) (Average 3.67)	<3.0	37	33.04	26	11	0.849
Diameter of Tumor (cm) (Average 3.67)	≥3.0	75	66.96	54	21	0.849
Differentiation	Well	12	10.71	7	5	0.458
	Moderate	82	73.21	61	21
	Poor	18	16.07	12	6
Tumor Status	T1, T2	97	86.61	66	31	0.044
Tumor Status	T3, T4	15	13.39	14	1	0.044
pTNM Stage	I, II	58	51.79	35	23	0.007
pTNM Stage	III	54	48.21	45	9	0.007
Node Status	N0, N1	59	52.68	36	23	0.010
Node Status	N2, N3	53	47.32	44	9	0.010
Pleural Invasion	(−)	43	38.39	24	19	0.004
Pleural Invasion	(+)	69	61.61	56	13	0.004
Post-operative relapse or metastasis	(−)	45	40.18	27	18	0.0028
Post-operative relapse or metastasis	(+)	67	59.82	53	14	0.0028

ISSN: 1471-2407