Fig. 1

Comparison of mRNA expression levels of a panel of genes between groups of a samples histologically assessed as tumor vs. tumor-free; b assessed as tumor with concomitant presence of ascites vs. no ascites; and c obtained after initial IPC (post, treated) vs. initial sampling before IPC within the first PIPAC procedures (pre, untreated). In each case, the samples were taken before the application of the chemotherapy aerosol. The magnitude of the mean expression level ratios of the groups is indicated by different levels of gray (from <1.5-fold, lightest gray to >8-fold, darkest gray). Arrowheads indicate whether the expression is higher (up) or lower (down) in the first group. The numbers of genes expressed higher/lower are indicated at the far right. Statistical significance of differences between the groups (Mann–Whitney rank sum test) is indicated by asterisks (***, p < 0.001; **, p < 0.01; *, p < 0.05). A color version of the figure is available in Additional file 7