Fig. 1
From: Shifting patterns of genomic variation in the somatic evolution of papillary thyroid carcinoma
Single Nucleotide Substitution Signatures. Pairwise comparison of each PTC with its matched ANT defines three subsets of SNSs, those unique to the PTC (right), those unique to the ANT (left), and the Common subset (middle). PTCs share between 57 and 88 % (mean 76 %) of their SNSs with the background ANT in which they arise. BRAF-mutated PTCs and patients over 45 years of age have a greater number of SNSs. (M = Male, F = Female; A = African American, C = Caucasian, H = Hispanic, O = Other; TN refers to the AJCC TNM staging system)