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Fig. 7 | BMC Cancer

Fig. 7

From: Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner

Fig. 7

Effect of GIRK1 variant overexpression on single cell velocities. a Cellular velocities for three representative cells during the entire observation interval of 72 h. Asterisks denote cell divisions. Upper: MCF-7eYFP; lower: MCF-7GIRK1a. b Graphical representation of mean cellular velocities for different experimental groups. WT: MCF-7WT; eYFP: MCF-7eYFP; hG1a: MCF-7GIRK1a; hG1c: MCF-7GIRK1c; hG1d: MCF-7GIRK1d. The median value is represented by the black line within the box, box margins represent 75 and 25 % percentiles, whiskers indicate 90 and 10 % percentiles, values outside the 10–90 % interval are plotted individually as crosses. The grey line represents the mean value. The number of individual cells is given in parenthesis besides each box. Statistical significant differences between groups are indicated. hG1a, as well as hG1c, differ from both WT, as well as from eYFP, statistically significant at the p < 0.001 level. hG1d differs from both hG1a, as well as from hG1c, statistically significant at the p < 0.001 level. Kruskal-Wallis one way analysis on ranks was used for analysis of statistical significance

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