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Fig. 5 | BMC Cancer

Fig. 5

From: Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner

Fig. 5

GIRK1 overexpression affects wound healing rate in a differential manner, depending on the variant tested. a Representative view of monolayers at different time intervals after scratching. Scale bars correspond to 200 μm. Left: control; right: GIRK1a overexpressors. b Wound healing rates (in % healing per h). WT: MCF-7WT; eYFP: MCF-7eYFP; hG1a: MCF-7GIRK1a; hG1c: MCF-7GIRK1c; hG1d: MCF-7GIRK1d. Mean values ± SEM were plotted (number of experiments is given in parenthesis above each bar). Statistical significances between groups are indicated. hG1a differs from eYFP statistically significant at the p < 0.05 level. hG1a differs from hG1d statistically significant at the p < 0.001 level. hG1c differs from hG1d statistically significant at the p < 0.01 level. Kruskal-Wallis one way analysis on ranks was used for analysis of statistical significance

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