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Table 1 Significant protein expressions of uPAS components and tumour-associated markers

From: uPAR enhances malignant potential of triple-negative breast cancer by directly interacting with uPA and IGF1R

Tumour marker 1

Tumour marker 2

p-values

uPAR

IGF1R

0.0011

Cathepsin B

0.0034

Cathepsin D

0.0075

c-Met

0.0229

IR

0.0215

Plasminogen

0.0105

uPA

PAI-1

≤0.00001

Cathepsin D

0.0187

Plasminogen

0.0237

Ki67

0.0004 (inverse)

IGF1R

IR

0.0020

Cathepsin B

0.0002

uPARAP

0.0168

Plasminogen

0.0237

Ki67

0.0120

PTEN

≤0.00001

PAI-1

Ki67

0.00006 (inverse)

c-Met

IR

0.0364

Plasminogen

0.0096

uPARAP

0.0097

Ki67

0.0486

IR

Plasminogen

0.0075

PTEN

0.0083

Ki67

0.0309

  1. Protein expressions were determined using IHC technique followed by statistical analyses. Correlations of parameters marked in bold are described within the text in more detail