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Table 1 Significant protein expressions of uPAS components and tumour-associated markers

From: uPAR enhances malignant potential of triple-negative breast cancer by directly interacting with uPA and IGF1R

Tumour marker 1 Tumour marker 2 p-values
uPAR IGF1R 0.0011
Cathepsin B 0.0034
Cathepsin D 0.0075
c-Met 0.0229
IR 0.0215
Plasminogen 0.0105
uPA PAI-1 ≤0.00001
Cathepsin D 0.0187
Plasminogen 0.0237
Ki67 0.0004 (inverse)
IGF1R IR 0.0020
Cathepsin B 0.0002
uPARAP 0.0168
Plasminogen 0.0237
Ki67 0.0120
PTEN ≤0.00001
PAI-1 Ki67 0.00006 (inverse)
c-Met IR 0.0364
Plasminogen 0.0096
uPARAP 0.0097
Ki67 0.0486
IR Plasminogen 0.0075
PTEN 0.0083
Ki67 0.0309
  1. Protein expressions were determined using IHC technique followed by statistical analyses. Correlations of parameters marked in bold are described within the text in more detail