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Table 4 Risk of death by uni- and multivariable Asp302His Cox-regression analyses

From: Prognostic relevance of caspase 8 -652 6N InsDel and Asp302His polymorphisms for breast cancer

Variable

Hazard Ratio

95 % CI

P

Univariate Analysis

 Asp302His

  Asp/Asp

1a

  

  Asp/His

1.607

0.96–2.69

0.071

  His/His

4.746

1.14–19.71

0.032

Multivariable Analysis

 Asp302His

   

  Asp/Asp

1a

  

  Asp/His

1.089

0.62–1.93

0.769

  His/His

4.889

1.10–21.76

0.037

 Age (per year)

1.002

0.98–1.02

0.839

 Tumor type

  ductal

1a

  

  lobular

1.659

0.87–3.15

0.123

  others

1.813

0.90–3.67

0.098

 Tumor stage

  T1

1a

  

  T2-4

1.849

1.11–3.07

0.017

 Nodal status

  negative

1a

  

  positive

3.652

2.13–6.27

<0.001

 Grade

  1

1a

  

  2

1.020

0.55–1.91

0.952

  3

1.648

0.82–3.30

0.158

  1. aReference group