From: Prognostic relevance of caspase 8 -652 6N InsDel and Asp302His polymorphisms for breast cancer
Variable | Hazard Ratio | 95Â % CI | P |
---|---|---|---|
Univariate Analysis | |||
 Asp302His | |||
  Asp/Asp | 1a |  |  |
  Asp/His | 1.607 | 0.96–2.69 | 0.071 |
  His/His | 4.746 | 1.14–19.71 | 0.032 |
Multivariable Analysis | |||
 Asp302His |  |  |  |
  Asp/Asp | 1a |  |  |
  Asp/His | 1.089 | 0.62–1.93 | 0.769 |
  His/His | 4.889 | 1.10–21.76 | 0.037 |
 Age (per year) | 1.002 | 0.98–1.02 | 0.839 |
 Tumor type | |||
  ductal | 1a |  |  |
  lobular | 1.659 | 0.87–3.15 | 0.123 |
  others | 1.813 | 0.90–3.67 | 0.098 |
 Tumor stage | |||
  T1 | 1a |  |  |
  T2-4 | 1.849 | 1.11–3.07 | 0.017 |
 Nodal status | |||
  negative | 1a |  |  |
  positive | 3.652 | 2.13–6.27 | <0.001 |
 Grade | |||
  1 | 1a |  |  |
  2 | 1.020 | 0.55–1.91 | 0.952 |
  3 | 1.648 | 0.82–3.30 | 0.158 |