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Fig. 5 | BMC Cancer

Fig. 5

From: MicroRNA-21 promotes proliferation, migration, and invasion of colorectal cancer, and tumor growth associated with down-regulation of sec23a expression

Fig. 5

Downregulation of Sec23A promotes the proliferation, migration, and invasion of CRC cells. a-c Sec23A knockdown increased migration, and invasion of SW-480 cells relative to negative controls (sh-NC). d-f Sec23A knockdown increased proliferation, migration, and invasion of DLD-1 cells relative to negative controls. In panels b, c, e, and f, photos on the left are representative images of migrated (b, e) and invaded cells on Matrigel membranes (c, f) while the graphs on the right indicate quantification of cells. * p < 0.05, ** p < 0.01

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