Fig. 4From: MicroRNA-21 promotes proliferation, migration, and invasion of colorectal cancer, and tumor growth associated with down-regulation of sec23a expressionSec23A knockdown increases expression of miR-21 in CRC cell lines. a Expression of Sec23A mRNA in untreated HT-29, SW-480, and DLD-1 cell lines. b-c Sec23A mRNA and protein expression was suppressed in Sec23A knockdown SW-480 cells. d-e Sec23A mRNA and protein expression was suppressed in Sec23A knockdown DLD-1 cells. Protein expression in these cells was quantified by densitometric analysis. f-g MiR-21 expression was increased in Sec23A knockdown SW-480 and DLD-1 cells. ** p < 0.01Back to article page