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Fig. 2 | BMC Cancer

Fig. 2

From: MicroRNA-21 promotes proliferation, migration, and invasion of colorectal cancer, and tumor growth associated with down-regulation of sec23a expression

Fig. 2

MiR-21 overexpression stimulates proliferation, migration, and invasion of CRC cells. a-c Inhibition of miR-21 in SW-480 by miR-21 inhibitor reduced cell proliferation, migration, and invasion relative to negative control (NC) and mock-treated cells (MOCK). d-f Up-regulation of miR-21 in DLD-1 by miR-21 mimic increased proliferation, migration, and invasion relative to negative control and mock-treated cells. In panels b, c, e, and f, photos on the left are representative images of migrated (b, e) and invaded cells on matrigel membranes (c, f), while the graphs on the right indicate quantification of cells. ** p < 0.01

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