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Fig. 2 | BMC Cancer

Fig. 2

From: Case report: small cell transformation and metastasis to the breast in a patient with lung adenocarcinoma following maintenance treatment with epidermal growth factor receptor tyrosine kinase inhibitors

Fig. 2

Hematoxylin–Eosin (HE) Staining of a Primary Lung Biopsy Specimen Revealed Adenocarcinoma(September 2012) (a). That Was Positive For TTF-1 (b) and Negative For Synaptophysin (c). Hematoxylin–Eosin Staining of a Secondary Biopsy Specimen in the Left Lingular Segment (July 2013) (d). Immunohistochemistry (IHC) Staining Showed High Expression of TTF-1 ( July 2013) (e). That Was Positive for Synaptophysin (g) and CD56 (f) (March 2014). Breast Mass Biopsy Specimens (X400) HE Staining Showed Small Cell Cancer Feature (March 2014) (h). Immunohistochemistry (IHC) Staining Showed High Expression of TTF-1 (i), Chomogranin A (j) and Synaptophysin (k), and a Negative Expression of estrogen receptor (ER) (l)

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BMC Cancer

ISSN: 1471-2407

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