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Table 5 Multivariate models for disease specific survival and disease free survival

From: Pre-treatment MRI minimum apparent diffusion coefficient value is a potential prognostic imaging biomarker in cervical cancer patients treated with definitive chemoradiation

Ā Ā 

Disease specific survival

Disease free survival

Variable

Category (*1)

N

HR (*2)

95Ā % CI

HR

95Ā % CI

Ā 

< 0.488

45

Ref

Ā 

Ref

Ā 

ADCmin

> 0.488

21

4.4

1.1ā€“18.5 (pā€‰=ā€‰0.043)

3.6

1.1ā€“12.1 (pā€‰=ā€‰0.035)

Ā 

< 0.827

25

Ref

Ā 

Ref

Ā 

ADCmean

> 0.827

41

277.3

0.0ā€“2.7 (pā€‰=ā€‰0.963)

4.9

0.6ā€“39.5 (pā€‰=ā€‰0.138)

Ā 

< 1.838

51

Ref

Ā 

Ref

Ā 

ADCmax

> 1.838

15

4.3

1.0ā€“19.3 (pā€‰=ā€‰0.056)

2.1

0.6ā€“7.3 (pā€‰=ā€‰0.255)

Ā 

< 0.148

16

Ref

Ā 

Ref

Ā 

ADCdev

> 0.148

50

202.5

0.0ā€“2.4 (pā€‰=ā€‰0.969)

2.7

0.4ā€“21.1 (pā€‰=ā€‰0.354)

  1. HR hazard ratio, CI confidence interval, Ref reference
  2. (*1) Cutoff values were defined by ROC curve analysis
  3. (*2) Each model was adjusted by FIGO staging (I/II vs III/IV)