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Table 3 Univariate analysis for disease specific survival and disease free survival

From: Pre-treatment MRI minimum apparent diffusion coefficient value is a potential prognostic imaging biomarker in cervical cancer patients treated with definitive chemoradiation

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Disease specific survival

Disease free survival

Variable

Category

n

3-y DSS

p-value

3-y DFS

p-value

FIGO

I / II

44

95.3

0.007

90.9

0.018

III / IV

22

72

72.7

Lymph node

Positive

40

79.1

0.015

74.9

0.024

Negative

26

100

100

Parametrial Invasion

Present

59

85.9

0.304

83

0.816

Absent

7

100

100

Vaginal Invasion

Present

47

84.3

0.265

82.9

0.850

Absent

19

94.7

89.5

Adjacent Structures Invasion

Present

21

71.1

0.005

69.3

0.015

Absent

45

95.3

93

GTV (a)

<114.48

41

97.6

0.001

95.1

0.003

>114.48

25

69.4

68

ADCmin (a)

<0.488

45

93.1

0.060

90.9

0.073

> 0.488

21

76.2

72.7

ADCmean (a)

< 0.827

25

100

0.017

96

0.037

> 0.827

41

79.3

77.9

ADCmax (a)

< 1.838

51

93.9

0.002

90.2

0.053

> 1.838

15

64.6

66

ADCdev (a)

< 0.148

16

100

0.088

93.8

0.221

> 0.148

50

83.2

81.9

  1. (a)Cutoff values were defined by ROC curve analysis