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Table 2 Mean ADC values according to tumor stage, lymph node involvement, and MRI assessed disease extent

From: Pre-treatment MRI minimum apparent diffusion coefficient value is a potential prognostic imaging biomarker in cervical cancer patients treated with definitive chemoradiation

Ā 

ADCmin

ADCmean

ADCmax

ADCdeviation

FIGO Stage

(pā€‰=ā€‰0.077)

(pā€‰=ā€‰0.227)

(pā€‰=ā€‰0.007)

(pā€‰=ā€‰0.070)

ā€ƒI-II (nā€‰=ā€‰44, being 22 with positive nodes)

0.375

0.855

1.485

0.224

ā€ƒIII-IV (nā€‰=ā€‰22, being 18 with positive nodes)

0.267

0.901

1.806

0.256

Lymph node

(pā€‰=ā€‰0.902)

(pā€‰=ā€‰0.092)

(pā€‰=ā€‰0.029)

(pā€‰=ā€‰0.154)

ā€ƒPositive (nā€‰=ā€‰40)

0.323

0.959

1.995

0.232

ā€ƒNegative (nā€‰=ā€‰26)

0.341

0.861

1.551

0.197

Parametrial Invasion

(pā€‰=ā€‰0.680)

(pā€‰=ā€‰0.810)

(pā€‰=ā€‰0.081)

(pā€‰=ā€‰0.492)

ā€ƒPresent (nā€‰=ā€‰59)

0.332

0.867

1.618

0.223

ā€ƒAbsent (nā€‰=ā€‰7)

0.404

0.898

1.371

0.177

Vaginal Invasion

(pā€‰=ā€‰0.190)

(pā€‰=ā€‰0.252)

(pā€‰=ā€‰0.203)

(pā€‰=ā€‰0.887)

ā€ƒPresent (nā€‰=ā€‰47)

0.311

0.848

1.624

0.198

ā€ƒAbsent (nā€‰=ā€‰19)

0.410

0.925

1.513

0.267

Adjacent structure invasion (rectum or bladder)

(pā€‰=ā€‰0.683)

(pā€‰=ā€‰0.184)

(pā€‰=ā€‰0.301)

(pā€‰=ā€‰0.829)

ā€ƒPresent (nā€‰=ā€‰21)

0.353

0.904

1.702

0.192

ā€ƒAbsent (nā€‰=ā€‰45)

0.339

0.854

1.542

0.231

Gross tumor volume (cc) a

(pā€‰=ā€‰0.172)

(pā€‰=ā€‰0.886)

(pā€‰=ā€‰0.147)

(pā€‰=ā€‰0.468)

ā€ƒā€‰>ā€‰114.48

0.295

0.862

1.674

0.237

ā€ƒā€‰<ā€‰114.48

0.383

0.877

1.508

0.206

  1. aCalculated by multiplication of the tumor measures (left-right, anterior-posterior, cranial-caudal)