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Fig. 7 | BMC Cancer

Fig. 7

From: Palmitate-induced ER stress increases trastuzumab sensitivity in HER2/neu-positive breast cancer cells

Fig. 7

Exogenous palmitate sensitizes HER2/neu-positive cells to trastuzumab. The HER2/neu-positive breast cancer cell lines SKBR3 and BT474 were treated with 22 μg/mL trastuzumab for 48 h either with palmitate (+ = 150 μM, ++ = 250 μM) or vehicle pre-treatment. C16 = palmitate. Nuclei were counted using the INCell Analyzer 2200. The data were normalized to 48 h trastuzumab alone and are presented as mean · SD. * = p · 0.05, ** = p · 0.01, *** = p · 0.001. One-way ANOVA with Bonferroni post-test. n = 3

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