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Table 2 Histological diagnosis and clinical management

From: “Safety and utility of percutaneous liver biopsy in hematopoietic stem cell transplant pediatric recipients: a retrospective study”

Clinical characteristics   N° (%) DSU (%) BMTU (%)
Total biopsy   68 (100) 12 (17.6) 56 (82.3)
Number of biopsy per patient 1 17 (37,7) 3 (17.6) 14 (82.3)
2 17 (37,7) 3 (17.6) 14 (82.3)
≥3 11 (24,4) 1 (9.1) 10 (90.9)
Histological diagnosis Drug Hepatotoxicity 2 (3,9) 1 (50.0) 1 (50.0)
AIH 1 (1,4) - 1 (100)
GVHD 24 (35,2) 4 (16,7) 20 (83.3)
GVHD + IO 19 (27,9) 3 16
GVHD + IO + Infection 1 (1,4) - 1 (100)
GVHD + IO + MD 2 (2,9) - 2 (100)
Infection 4 (5,8) 1 (25.0) 3 (75.0)
IO + Drug toxicity 4 (5,8) 1 (25.0) 3 (75.0)
IO + Infection 1 (1,4) 1 (100) -
IO + MD 1 (1,4) - 1 (100)
Iron overload 6 (8,8) 1 (16.7) 5 (83.3)
Metabolic Disorders 2 (2,9) 0 2 (100)
Normal 1 (1,4) 0 1 (100)
Changes in clinical management No 32 (47,1) 3 (9.4) 29 (90.6)
Yes 36 (52,9) 9 (25.0) 27 (75.0)
Outcome Improved 33 (48,5) 6 (18.2) 27 (81.8)
Recovered 13 (19,1) 2 (15.4) 11 (84.6)
Not changed 19 (27,9) 2 (10.5) 17 (89.5)
Worsened 1 (1,4) 1 (100) 0
Death 2 (2,9) 1 (50.0) 1 (50.0)
  1. Histological diagnosis and clinical management. DSU Day surgery unit, BMTU Bone marrow transplant unit, AIH autoimmune hepatitis, GVHD Graft versus host disease, IO Iron overload, MD Metabolic disease