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Table 3 Univariate analysis of overall mortality and disease-specific mortality

From: The association of infrared imaging findings of the breast with prognosis in breast cancer patients: an observational cohort study

  

Overall mortality

Disease-specific mortality

Variable

n

HR

95 % CI

p

HR

95 % CI

p

Age ≤ 50 years

51

1

 

0.92

1

 

0.45

Age > 50 years

92

0.96

0.44–2.08

1.49

0.54–4.12

Postmenopausal

85

1.06

0.50–2.27

0.87

0.94

0.38–2.34

0.89

Clinical stage

   

<0 .0001

  

<0.0001

 stages I & II

101

1

 

1

 

 Stage III

31

3.00

1.24–7.24

1.92

0.58–6.39

 Stage IV

11

10.89

4.35–27.23

14.02

5.05–38.94

Histology

   

0.14

  

0.92

 IDC

130

1

 

1

 

 ILC

8

2.94

1.02–8.51

1.06

0.14–7.99

 Other subtypes

5

1.07

0.14–7.95

1.51

0.20–11.35

IDC tumor grade

   

0.80

  

0.86

 Grade 1

15

1

 

1

 

 Grade 2

68

1.84

0.23–14.71

0.58

0.32–1.04

 Grade 3

39

2.10

0.25–17.96

0.40

0.21–0.79

Molecular subtype

   

0.39

  

0.36

 Luminal

78

1

  

1

 

 HER2-enriched

32

1.73

0.71–4.24

 

0.87

0.23–3.22

 Triple-negative

33

1.65

0.67–4.03

 

1.90

0.71–5.11

IR signs a

      

 IR1

   

0.03

  

0.04

 IR1 = 0

109

1

 

1

 

 IR1 = 1

34

2.29

1.07–4.89

2.57

1.03–6.40

IR2

   

0.75

  

0.42

 IR2 = 0

61

1

 

1

 

 IR2 = 1

82

0.89

0.42–1.87

0.69

0.28–1.70

IR 3

   

0.33

  

0.53

 IR3 = 0

12

1

 

1

 

 IR3 = 1

131

2.71

0.37–19.95

1.91

0.26–14.34

IR 4

   

0.50

  

0.22

 IR4 = 0

114

1

 

1

 

 IR4 = 1

29

1.34

0.57–3.16

1.83

0.70–4.81

IR 5

   

0.47

  

0.93

 IR5 = 0

26

1

 

1

 

 IR5 = 1

117

1.48

0.51–4.27

0.95

0.32–2.87

  1. Estimated by univariate Cox proportional hazards analysis
  2. HR hazard ratio, 95 % CI 95 % confidence interval, IDC invasive ductal carcinoma, ILC invasive lobular carcinoma; IR: infrared
  3. aIR imaging signs are defined in Table 1; 0 = negative, 1 = positive