Table 2 Progression-free survival – univariate analysis

Age

1.0

0.95–1.9

0.12

TN stage

T2–3

T4

1.9

1.0–3.9

0.06

N0

N1–2

0.97

0.38–2.5

0.95

Baseline CEA

≤ULN

>ULN

1.4

0.72–2.8

0.31

ypTN stage

ypT0–2

ypT3–4

4.2

1.9–9.5

<0.001

ypN0

ypN1–2

3.7

1.8–7.5

<0.001

TRG score

TRG1–2

TRG3–5

2.4

1.2–4.7

0.01

Post-NACT

LCN2

2.2

1.0–4.8

0.05

MMP9

2.8

1.5–5.9

<0.01

Post-CRT

LCN2

2.3

1.0–5.2

0.06

MMP9

2.9

1.1–3.4

0.03