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Fig. 2 | BMC Cancer

Fig. 2

From: Circulating proteins in response to combined-modality therapy in rectal cancer identified by antibody array screening

Fig. 2

Functional coupling between proteins that changed in patients’ circulation during neoadjuvant therapy. Proteins are depicted by their gene symbols. Yellow nodes: proteins whose serum levels significantly differed from baseline following induction neoadjuvant chemotherapy (post-NACT) and sequential chemoradiotherapy (post-CRT) and at treatment evaluation. Non-yellow nodes: proteins not present in the query list but predicted as interacting with the significantly altered proteins at the specific sampling point. Encircled nodes: proteins further analyzed

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