Fig. 8

Effects of the compounds on the growth of WI-38 cells. a WI-38 cells cultured in the presence of test compounds at 10 μM for 3 days were harvested, and viable cells were counted using trypan blue exclusion assays. Data are presented as the mean ± SE of four independent experiments. b WI-38 cells cultured in the presence of test compounds (C1, C2, and C3) at 10 μM for 12 h were harvested, and then cell cycle profiles were analyzed. c Cytotoxic effects of compound C1 and its derivatives with varying alkyl chain lengths are shown. WI-38 cells cultured in the presence of test compounds at 10 μM for 3 days were harvested, and viable cells were counted using trypan blue exclusion assays. Data are presented as the mean ± SE of four independent experiments