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Fig. 1 | BMC Cancer

Fig. 1

From: p53-independent structure-activity relationships of 3-ring mesogenic compounds’ activity as cytotoxic effects against human non-small cell lung cancer lines

Fig. 1

Effects of test compounds on the growth of non-small cell lung cancer (NSCLC) cells. a The structures of the test compounds are shown. b, de NSCLC cells cultured in the presence of compounds C1–C7 at 10 μM for 3 days were harvested, and viable cells were counted using trypan blue exclusion assays. Dotted lines indicate the dimethyl sulfoxide control. Data are presented as the mean ± SE of 3 independent experiments. c A549 cells cultured in the presence of compounds C1–C2 at 10 μM for 1–3 days were harvested, and viable cells were counted using trypan blue exclusion assays. Results are shown as relative value against input cell number. Data are presented as the mean ± SE of 3 independent experiments. f Structural formulae of C1 and its derivatives with differing alkyl chain lengths and cytotoxic effects against A549 cells [left panel] and the other NSCLC cells [light panel]; data are presented as mean ± SE of 3 independent experiments. g The logP values of test compounds are shown

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