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Fig. 7 | BMC Cancer

Fig. 7

From: PAC down-regulates estrogen receptor alpha and suppresses epithelial-to-mesenchymal transition in breast cancer cells

Fig. 7

PAC suppresses the paracrine procarcinogenic effects of breast cancer cells. SFCM from MDA-MB-231 cells either exposed to DMSO (DMSO-MDA-SFCM) or challenged with PAC (10 μM) (PAC-MDA-SFCM) was used for indirect co-culturing of NBF-1 fibroblasts cells for 24 h, and then cell proliferation (a) as well as migration/invasion (b) were assessed using the real time RTCA-DP xCELLigence System as described in Fig. 4. Error bars represent means ± S.D from three different experiments; *, P ≤ 0.001

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