Comparison of detection methods and follow-up study on the tyrosine kinase inhibitors therapy in non-small cell lung cancer patients with ROS1 fusion rearrangement

Table 4 Comparison of FISH and IHC in ROS1 rearrangement detection

	FISH ROS1 fusion positive	FISH ROS1 fusion negative	P.	Kappa Value
IHC ROS1 2-3+	10	1	< 0.01^a	0.950
IHC ROS1-, 1+	0	227
IHC extent ≥ 60 %	10	9	< 0.01^a	0.672
IHC extent < 60 %	0	219
IHC H-score ≥ 150	10	0	< 0.01^a	1.000
IHC H-score < 150	0	228

ISSN: 1471-2407