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Fig. 1 | BMC Cancer

Fig. 1

From: Is monitoring of plasma 5-fluorouracil levels in metastatic / advanced colorectal cancer clinically effective? A systematic review

Fig. 1

Reconstructed Kaplan Meier analyses (95 % CI) of the three dual arm studies. Capitain [39] used a FOLFOX6 regimen, Kline [40] FOLFOX6 or FOLFIRI regimens (the reported logrank test for pharmacokinetic versus body surface area was p 0.161), and Gamelin 2008 [38] an 5-fluorouracil + folinic acid (FO) regimen with 5-fluorouracil infused over 8 h (the reported logrank test for pharmacokinetic versus body surface area was p 0.08). The circular data points in the Capitain figure represent the reported medians for overall survival and progression-free survival in the body surface area arm and the dashed lines are Weibull fits using the same shape parameters as for Weibull fits to the pharmacokinetic arm

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