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Table 8 Correlations between the clock genes and common tumour markers

From: Expression of circadian clock genes and proteins in urothelial cancer is related to cancer-associated genes

Genes encoding p-value Correlation coeff, C Genes encoding p-value Correlation coeff, C
BMAL - TP53 0.031 0.415 CSNK1A1 -TP53 0.005 0.527
- P16 0.001 0.601 - PTEN 0.001 0.582
- PTEN 0.029 0.419 - KRAS 0.004 0.536
- KRAS 0.000 0.670 - NRAS 0.000 0.635
- NRAS 0.000 0.694 -UPAR 0.001 0.611
- PAI-1 0.003 0.546
CLOCK - KRAS 0.000 0.634 - KRT7 0.007 0.504
- NRAS 0.005 0.525 - KRT5 0.005 0.521
PER1 - UPAR 0.031 0.416 CRY-1 - P16 0.040 0.397
- PAI-1 0.047 0.386 - EGFR 0.035 0.407
- NRAS 0.001 0.584
PER2 - PTEN 0.017 0.455 CSNK1E - TP53 0.008 0.499
- PAI-1 0.011 0.480 - P16 0.013 0.471
- KRT7 0.011 0.480 - PTEN 0.021 0.442
- KRT5 0.044 0.390 - KRAS 0.008 0.497
- KRT10 0.034 0.409 - NRAS 0.000 0.659
-UPAR 0.010 0.487
- PAI-1 0.033 0.412
- KRT7 0.033 0.412
PER3 - KRT5 0.019 0.448     
- KRT14 0.045 0.389
  1. The correlation coefficients: C < 0.3: poor correlation, 0.3 < C < 0.5: fair correlation, 0.6 < C < 0.8: moderately strong correlation and 0.8 < C: Very strong correlation
  2. The genes listed in the right column of the table are found to correlate to the underlined genes in the corresponding left column