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Fig. 3 | BMC Cancer

Fig. 3

From: Expression of circadian clock genes and proteins in urothelial cancer is related to cancer-associated genes

Fig. 3

Relative mRNA quantity of PER1, PER2, PER3 and CRY2. Real-time quantitative PCR expression levels normalized against the endogenous control β-actin (ACTB). The figure gives the comparison between 27 tumour and matched benign bladder tissue samples. Columns, median; bars, a: PER1, b: PER2, c: PER3 and d: CRY2. The relative gene expression of all four genes was significantly elevated in the benign versus malignant bladder tissue. The changes were consistent for each pair of tumour - neighbouring mucosa, indicated by the p-value of the statistical test (non-parametric paired samples Mann-Whitney test)

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