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Table 6 Assessment of associations between proteins plasma membrane expression in CRC lymph node metastasis and clinical data

From: Significance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis

  MCT1 MCT4 CD147 GLUT1
n Positive (%) p n Positive (%) p n Positive (%) p n Positive (%) p
Sex
 Male 77 25 (32.5) 0.581 74 46 (62.2) 0.317 77 62 (91.9) 0.159 71 47 (76.7) 0.523a
 Female 40 11 (27.5)   40 21 (52.5)   40 34 (82.4)   38 22 (86.4)  
Age (years)
 ≤45 10 3 (30.0) 1.000a 8 4 (50.0) 0.715a 9 8 (75.0) 0.228a 8 5 (40.0) 0.053a
 >45 107 33 (30.8)   106 63 (59.4)   108 88 (89.8)   101 64 (82.8)  
Presentation
 Asymptomatic 19 6 (31.6) 0.933 18 8 (44.4) 0.178 22 18 (88.9) 1.000a 16 10 (60.0) 0.109a
 Symptomatic 98 30 (30.6)   96 59 (61.5)   95 78 (88.5)   93 59 (83.1)  
Localization
 Colon 94 28 (29.8) 0.642 91 58 (63.7) 0.032 95 81 (88.9) 0.681a 88 57 (80.7) 0.698a
 Rectum 23 8 (34.8)   23 9 (39.1)   22 15 (86.7)   21 12 (75.0)  
Macroscopic Appearence
 Polypoid 47 14 (29.8) 0.596 47 27 (57.4) 0.534 45 36 (86.1) 0.701 45 25 (84.0) 0.500
 Ulcerative 31 7 (22.6)   30 20 (66.7)   34 28 (85.7)   28 20 (70.0)  
 Infiltrative 13 5 (38.5)   13 6 (46.2)   12 11 (90.9)   11 6 (100.0)  
 Exophytic 14 6 (42.9)   13 7 (53.8)   14 12 (100.0)   14 11 (81.8)  
 Vilosous 1 0 (0.0)   1 0 (0.0)   1 1 (100.0)   1 1 (100.0)  
CEA (ng/mL)
 <5 71 21 (29.6) 0.354 67 42 (62.7) 0.434 68 56 (91.1) 0.120 65 40 (85.0) 0.237a
 ≥5 25 5 (20.0)   26 14 (53.8)   26 23 (78.3)   23 13 (69.2)  
  1. aComparisons were examined for statistical significance using Fisher’s exact test (when n < 5)