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Table 5 Late toxicity profiles of cisplatin versus carboplatin

From: Combined chemoradiation of cisplatin versus carboplatin in cervical carcinoma: a single institution experience from Thailand

Late toxicity cisplatin (N = 137) carboplatin (N = 76) p-value
Chronic GI    0.331
Grade 0 103(75.2 %) 63(82.9 %)
Grade 1 13(9.5 %) 3(3.9 %)
Grade 2 15(10.9 %) 5(6.6 %)
Grade 3 2(1.5 %) 3(3.9 %)
Grade 4 4(2.9 %) 2(2.6 %)
Chronic GU    0.206
Grade 0 122(89.1 %) 69(90.8 %)
Grade 1 6(4.4 %) 1(1.3 %)
Grade 2 6(4.4 %) 1(1.3 %)
Grade 3 1(0.7 %) 3(3.9 %)
Grade 4 2(1.5 %) 2(2.6 %)
Chronic skin    1.00
Grade 0 135(98.5 %) 75(98.7 %)
Grade 1 1(0.7 %) 0
Grade 2 1(0.7 %) 1(1.3 %)
Subcutaneous tissue    0.849
Grade 0 117(85.4 %) 65(85.5 %)
Grade 1 13(9.5 %) 6(7.9 %)
Grade 2 7(5.1 %) 5(6.6 %)
Vaginal obstruction    0.281
Grade 0 101(73.7 %) 58(76.3 %)
Grade 1 17(12.4 %) 9(11.8 %)
Grade 2 18(13.1 %) 6(7.9 %)
Grade 3 1(0.7 %) 3(3.9 %)