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Table 4 Acute toxicity of cisplatin versus carboplatin

From: Combined chemoradiation of cisplatin versus carboplatin in cervical carcinoma: a single institution experience from Thailand

Acute toxicity cisplatin (N = 137) carboplatin (N = 76) P-value
Anemia    0.026
Grade 0 87(63.5 %) 57(75.0 %)
Grade 1 19(13.9 %) 10(13.2 %)
Grade 2 28(20.7 %) 5(6.6 %)
Grade 3 3(2.2 %) 4(5.3 %)
Neutropenia    0.044
Grade 0 84(61.3 %) 57(75 %)
Grade 1 25(18.2 %) 14(18.4 %)
Grade 2 25(18.2 %) 5(6.6 %)
Grade 3 3(2.2 %) 0
Thrombocytopenia    0.392
Grade 0 128(93.4 %) 72(94.7 %)
Grade 1 4(2.9 %) 0
Grade 2 4(2.9 %) 4(5.3 %)
Grade 3 1(0.7 %) 0
Renal toxicity    0.031
Grade 0 112(81.8 %) 73(96.5 %)
Grade 1 8(5.8 %) 1(1.3 %)
Grade 2 10(7.3 %) 1(1.3 %)
Grade 3 7(5.1 %) 1(1.3 %)
Skin toxicity    0.45
Grade 0 139(94.9 %) 75(98.7 %)
Grade 1 4(2.9 %) 1(1.3 %)
Grade 2 3(2.2 %) 0
Proctitis    0.94
Grade 0 122(89.1 %) 67(88.2 %)
Grade 1 9(6.6 %) 6(7.9 %)
Grade 2 6(4.4 %) 3(3.9 %)
Cystitis    0.066
Grade 0 130(94.9 %) 67(88.2 %)
Grade 1 7(5.1 %) 7(9.2 %)
Grade 2 0 2(2.6 %)