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Table 4 Univariate and multivariate analyses to determine the risk factor for ESCC recurrence

From: CXCL12 expression promotes esophageal squamous cell carcinoma proliferation and worsens the prognosis

  Recurrence-free survival
  Univariate Multivariate
Characteristic p value HR (95 % CI) p value
Positive CXCL12 expression (+/−) 0.021 5.12 (1.54–17.01) 0.008
Positive CXCR4 expression (+/−) 0.97   
pT (≥pT3 vs < pT3) 0.10   
Lymph node metastasis (+/−) 0.005   
Lymphatic invasion (+/−) 0.002 1.84 (1.24–2.72) 0.002
Vessel invasion (+/−) 0.004 2.13 (1.03–4.39) 0.04
  1. HR hazard ratio, CI confidence interval