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Table 6 Diagnosis of intermediate- and/or high-risk endometrial cancers by preoperative assessment (MRI and endometrial sample) (n = 91)

From: Are preoperative histology and MRI useful for classification of endometrial cancer risk?

 

Endometrial sample

MRI

Combination (MRI and histology)

 

Type 2

Grade 3

FIGO Stage > IA

High risk

Intermediate and high risk

Sensitivity (%) [95 % CI]

63.6 [35.4–84.8]

30.0 [10.8–60.3]

78.3 [64.4–87.7]

47.7 [33.8–62.1]

70.0 [58.0–80.8]

Specificity (%) [95 % CI]

95.0 [87.8–98.0]

98.4 [91.7–99.7]

88.9 [76.5–95.2]

93.6 [82.8–97.8]

81.8 [65.6–91.4]

PPV (%) [95 % CI]

63.6 [35.4–84.8]

75.0 [30.1–95.4]

87.8 [74.5–94.7]

87.5 [69.0–95.7]

87.2 [74.8–94.0]

NPV (%) [95 % CI]

95.0 [87.8–98.0]

90.0 [80.8–95.1]

80.0 [67.0–88.8]

65.7 [53.7–75.9]

61.4 [46.6–74.3]

+LR [95 % CI]

12.7 [4.4–36.5]

19.2 [2.2–166.9]

7.0 [3.0–16.3]

7.5 [2.4–23.3]

3.8 [1.8–8.2]

-LR [95 % CI]

0.4 [0.1–0.8]

0.7 [0.4–1.1]

0.2 [0.1–0.4]

0.6 [0.4–0.7]

0.3 [0.2–0.5]

  1. PPV positive predictive value, NPV negative predictive value, +LR positive likelihood ratio, −LR negative likelihood ratio