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Table 6 Diagnosis of intermediate- and/or high-risk endometrial cancers by preoperative assessment (MRI and endometrial sample) (n = 91)

From: Are preoperative histology and MRI useful for classification of endometrial cancer risk?

  Endometrial sample MRI Combination (MRI and histology)
  Type 2 Grade 3 FIGO Stage > IA High risk Intermediate and high risk
Sensitivity (%) [95 % CI] 63.6 [35.4–84.8] 30.0 [10.8–60.3] 78.3 [64.4–87.7] 47.7 [33.8–62.1] 70.0 [58.0–80.8]
Specificity (%) [95 % CI] 95.0 [87.8–98.0] 98.4 [91.7–99.7] 88.9 [76.5–95.2] 93.6 [82.8–97.8] 81.8 [65.6–91.4]
PPV (%) [95 % CI] 63.6 [35.4–84.8] 75.0 [30.1–95.4] 87.8 [74.5–94.7] 87.5 [69.0–95.7] 87.2 [74.8–94.0]
NPV (%) [95 % CI] 95.0 [87.8–98.0] 90.0 [80.8–95.1] 80.0 [67.0–88.8] 65.7 [53.7–75.9] 61.4 [46.6–74.3]
+LR [95 % CI] 12.7 [4.4–36.5] 19.2 [2.2–166.9] 7.0 [3.0–16.3] 7.5 [2.4–23.3] 3.8 [1.8–8.2]
-LR [95 % CI] 0.4 [0.1–0.8] 0.7 [0.4–1.1] 0.2 [0.1–0.4] 0.6 [0.4–0.7] 0.3 [0.2–0.5]
  1. PPV positive predictive value, NPV negative predictive value, +LR positive likelihood ratio, −LR negative likelihood ratio