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Table 4 Diagnosis of grade 3 endometrial cancers, among endometrioid-type cancers, by preoperative endometrial sample (n = 74)

From: Are preoperative histology and MRI useful for classification of endometrial cancer risk?

  Cornier® Pipelle (n = 41) Curettage with hysteroscopy (n = 33) Both types of sampling (n = 74)
Sensitivity (%) [95 % CI] 28.6 [8.2–64.1] 33.3 [6.1–79.2] 30.0 [10.8–60.3]
Specificity (%) [95 % CI] 97.1 [85.1–99.5] 100 [88.6–100] 98.4 [91.7–99.7]
PPV (%) [95 % CI] 66.7 [20.8–93.9] 100 [20.7–100] 75.0 [30.1–95.4]
NPV(%) [95 % CI] 86.8 [72.7–94.2] 93.7 [79.9–98.3] 90.0 [80.8–95.1]
+LR [95 % CI] 9.7 [1.0–92.9] NA 19.2 [2.2–166.9]
-LR [95 % CI] 0.7 [0.5–1.2] NA 0.7 [0.4–1.1]
Overestimation (%) 2.4* 0.0* 1.3
Accuracy rate (%) 85.4* 93.9* 89.2
Underestimation (%) 12.2* 6.1* 9.5
  1. PPV positive predictive value, NPV negative predictive value, +LR positive likelihood ratio, −LR negative likelihood ratio, NA not applicable
  2. *There was no significant difference between the pipelle group and the curettage group (p = 0.555)