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Table 4 Diagnosis of grade 3 endometrial cancers, among endometrioid-type cancers, by preoperative endometrial sample (n = 74)

From: Are preoperative histology and MRI useful for classification of endometrial cancer risk?

 

Cornier® Pipelle (n = 41)

Curettage with hysteroscopy (n = 33)

Both types of sampling (n = 74)

Sensitivity (%) [95 % CI]

28.6 [8.2–64.1]

33.3 [6.1–79.2]

30.0 [10.8–60.3]

Specificity (%) [95 % CI]

97.1 [85.1–99.5]

100 [88.6–100]

98.4 [91.7–99.7]

PPV (%) [95 % CI]

66.7 [20.8–93.9]

100 [20.7–100]

75.0 [30.1–95.4]

NPV(%) [95 % CI]

86.8 [72.7–94.2]

93.7 [79.9–98.3]

90.0 [80.8–95.1]

+LR [95 % CI]

9.7 [1.0–92.9]

NA

19.2 [2.2–166.9]

-LR [95 % CI]

0.7 [0.5–1.2]

NA

0.7 [0.4–1.1]

Overestimation (%)

2.4*

0.0*

1.3

Accuracy rate (%)

85.4*

93.9*

89.2

Underestimation (%)

12.2*

6.1*

9.5

  1. PPV positive predictive value, NPV negative predictive value, +LR positive likelihood ratio, −LR negative likelihood ratio, NA not applicable
  2. *There was no significant difference between the pipelle group and the curettage group (p = 0.555)