Table 1 Clinicopathologic parameters, FOXM1 expression and survival analysis

Sex

 Male

44

13

31

 Female

62

Male vs. female

0.0028*

0.3047

17

45

0.811

Age

  < 20

19

4

15

  ≥ 20

87

20 < vs. ≥20

0.0189*

0.2499

26

61

0.4279

Chemotherapy

 Yes

25

6

19

 No

25

Yes vs. No

0.3431

0.8037

4

21

0.4783

 N.A.

56

Fusion gene type

 SS18-SSX1

30

11

19

 SS18-SSX2

14

SSX1 vs. SSX2

0.6271

0.8581

3

11

0.3736

 N.A.

62

Depth

 Superficial

13

5

8

 Deep

91

Deep vs. Superficial

0.4441

0.9057

25

66

0.4243

 N.A.

2

Size,cm

  < 5

40

8

32

 5≥

62

<5 vs. 5≤

0.0012*

0.0335*

22

40

0.0885

 N.A.

4

Histological subtype

 Mono

69

22

47

 Bi

26

Mono vs. bi

0.4225

0.9701

3

23

0.0335*

 Poor

3

1

2

 Undetermined

8

Necrosis

 None

56

13

43

  ≤ 50 %

26

Necrosis (+) vs. (−)

<0.001*

0.0012*

9

17

0.1526

  > 50 %

15

6

9

 N.A.

9

Mitotic count

  ≥ 10/10HPF

70

12

58

  < 10/10HPF

31

≥10 vs. <10/10HPF

0.0344*

0.0056*

17

14

0.0002*

 N.A.

5

AJCC stage

 II

39

II vs. III

0.0304*

0.3734

11

28

0.72

 III

44

III vs. IV

<0.001*

-

14

30

0.6579

 IV

13

5

8

 N.A.

10

FNCLCC

 2

69

18

51

 3

23

2 vs. 3

<0.001*

<0.001*

10

13

0.123

 N.A.

14

FOXM1

 Positive

30

 Negative

76

Positive vs. negative

0.0128*

0.0043*

-

-

-