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Fig. 4 | BMC Cancer

Fig. 4

From: Prognostic significance of FOXM1 expression and antitumor effect of FOXM1 inhibition in synovial sarcomas

Fig. 4

Thiostrepton reduced FOXM1 expression in the SS cell lines, producing diminished cell viability. a SS cell lines treated with 1 μM thiostrepton for 48 h and 72 h showed decreased FOXM1 protein on Western blots. b Treatment of SS cell lines with increasing quantities of Thiostrepton for 72 h resulted in reduced numbers of viable cells compared to diluent controls. c and d Proliferation of SS cell lines treated with 1 μM thiostrepton, 5 ng/mL DOX, or their combination. The cell lines treated with the combination of both drugs showed lower proliferation than those treated with each drug individually (c: SYO-I, d: HS-SY-II). *P < 0.05 by Steel-Dwass multiple comparison test

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