Fig. 1

Estimated Kaplan-Meier curves for distant metastasis-free and overall survival categorized by the serum level of (a) osteopontin, (b) thrombospondin-1 and (c) their combination. The osteopontin high group was defined as the top 20 % patient population with the highest values in osteopontin level and the osteopontin low group represented the rest of the population. Thrombospondin-1 low group was defined as the top 10 % patient population with the lowest values in thrombospondin-1 level and thrombospondin-1 high group represented the rest of the population