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Fig. 5 | BMC Cancer

Fig. 5

From: EHD1 confers resistance to cisplatin in non-small cell lung cancer by regulating intracellular cisplatin concentrations

Fig. 5

Determination of the CDDP concentrations in NSCLC cells treated with CDDP. a Chromatograms of extract (CDDP) from NSCLC cellular lysate (4, 8, 12, and 24Ā h). b Quantification of CDDP in lysate extracted from EHD1-overexpressing and control cell lines (4, 8, 12, and 24Ā h). c Chromatograms of extract (CDDP) from CDDP-resistant NSCLC cellular lysate (4, 8, 12, and 24Ā h). d Quantification of CDDP in lysate extracted from EHD1 knockdown and control cell lines (4, 8, 12, and 24Ā h). e Chromatograms of extract (CDDP) from NSCLC cellular lysate (10, 20, and 50Ā Ī¼M). f Quantification of CDDP in lysate extracted from EHD1-overexpressing and control cell lines (10, 20, 50Ā Ī¼M). g Chromatograms of extract (CDDP) from CDDP-resistant NSCLC cellular lysate (10, 20, and 50Ā Ī¼M). h Quantification of CDDP in lysate extracted from EHD1 knockdown and control cell lines (10, 20, and 50Ā Ī¼M)

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