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Fig. 4 | BMC Cancer

Fig. 4

From: New anti-cancer chemicals Ertredin and its derivatives, regulate oxidative phosphorylation and glycolysis and suppress sphere formation in vitro and tumor growth in EGFRvIII-transformed cells

Fig. 4

Ertredin suppressed NIH3T3/EGFRvIII (left) and NIH3T3/EGFRwt (right) tumorigenicity in nude mice. a Macroscopic tumor appearance at day 17 (NIH3T3/EGFRvIII) and day 18 (NIH3T3/EGFRwt). b Weights of tumors at day 17 (NIH3T3/EGFRvIII) and day 18 (NIH3T3/EGFRwt). c Time-dependent changes in body weights of mice transplanted with NIH3T3/EGFRvIII (left) and NIH3T3/EGFRwt. P values in two-tailed paired student t-test are shown: *p < 0.05; **p < 0.01; ***p <0.001

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BMC Cancer

ISSN: 1471-2407

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