Cross-reactivity profiles of hybrid capture II, cobas, and APTIMA human papillomavirus assays: split-sample study

BMC Cancer

Table 6 Genotype distribution in cross-reacting samples on cobas

Genotype	cobas test result
Genotype	Genotype 16	Genotype 18	Other high-risk genotypes	16 and 18	16 and other high-risk	18 and other high-risk	16, 18, and other high-risk	Total
6	1	0	6	0	0	0	0	7
11	0	0	1	0	0	0	0	1
26	0	0	1	0	0	0	0	1
42	2	0	2	0	0	0	0	4
44	0	0	2	0	0	0	0	2
53	0	1	7	0	0	0	0	8
54	1	1	2	0	0	0	0	4
61	3	1	7	0	0	0	0	11
62	0	0	6	0	0	0	0	6
70	0	2	10	0	0	0	0	12
72	0	0	1	0	0	0	0	1
81	1	0	3	0	0	1	0	5
82	1	0	4	0	0	0	0	4
83	0	0	6	0	0	0	0	6
84	0	0	6	0	1	0	0	7
# Samples with a positive test result	168 (100 %)	56 (100 %)	858 (100 %)	6 (100 %)	167 (100 %)	71 (100 %)	19 (100 %)	1345 (100 %)
# Samples with only low-risk genotypes	8 (4.8 %)	4 (7.1 %)	48 (5.6 %)	0 (0.0 %)	1 (0.6 %)	1 (1.4 %)	0 (0.0 %)	62 (4.6 %)
# Samples with no detected genotype	26 (15.5 %)	10 (17.9 %)	116 (13.5 %)	0 (0.0 %)	8 (4.8 %)	2 (2.8 %)	0 (0.0 %)	162 (12.0 %)

No woman had a cross-reacting sample on cobas because of genotypes 40, 43, 71, 73, 85, or 89

ISSN: 1471-2407