Table 2 Characteristics of cross-reacting samples in 5022 women
| Â | Total (any of the three assays) | HC2 | cobas | APTIMA |
|---|---|---|---|---|
Cross-reactivity to low-risk genotypes | Â | |||
 Age |  | |||
  <30 years (n = 1683) | 75 | 51 (3.0 %) | 34 (2.0 %) | 15 (0.9 %) |
  ≥30 years (n = 3339) | 82 | 58 (1.7 %) | 28 (0.8 %) | 20 (0.6 %) |
 Concurrent cytology | ||||
  Normal (n = 4630) | 116 | 71 (1.5 %) | 56 (1.2 %) | 29 (0.6 %) |
  Abnormal (n = 367) | 40 | 37 (10.1 %) | 6 (1.6 %) | 6 (1.6 %) |
  Inadequate (n = 25) | 1 | 1 (4.0 %) | 0 (0.0 %) | 0 (0.0 %) |
 Histology outcome | ||||
  CIN2 (n = 60) | 2 | 2 (3.3 %) | 0 (0.0 %) | 1 (1.7 %) |
  CIN3 or worse (n = 118)a | 4 | 4 (3.4 %) | 2 (1.7 %) | 1 (0.8 %) |
Cross-reactivity to unconfirmed genotypes | Â | |||
 Age |  | |||
  <30 years (n = 1683) | 73 | 15 (0.9 %) | 56 (3.3 %) | 15 (0.9 %) |
  ≥30 years (n = 3339) | 150 | 34 (1.0 %) | 106 (3.2 %) | 41 (1.2 %) |
 Concurrent cytology | ||||
  Normal (n = 4630) | 214 | 44 (1.0 %) | 157 (3.4 %) | 54 (1.2 %) |
  Abnormal (n = 367) | 7 | 4 (1.1 %) | 3 (0.8 %) | 2 (0.5 %) |
  Inadequate (n = 25) | 2 | 1 (4.0 %) | 2 (8.0 %) | 0 (0.0 %) |
 Histology outcome | ||||
  CIN2 (n = 60) | 0 | 0 (0.0 %) | 0 (0.0 %) | 0 (0.0 %) |
  CIN3 or worse (n = 118)a | 1 | 1 (0.8 %) | 1 (0.8 %) | 1 (0.8 %) |