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Table 3 Correlation between loss of heterozygosity of chromosome 9p and various tumour characteristics in clinically localized renal cell carcinoma

From: Microsatellite alteration and immunohistochemical expression profile of chromosome 9p21 in patients with sporadic renal cell carcinoma following surgical resection

  

D9S916

D9S974

D9S942

D9S1814

D9S171

Variables

 

Normal

LOH

p=

Normal

LOH

p=

Normal

LOH

p=

Normal

LOH

p=

Normal

LOH

p=

Tumour size

Mean

5.3

4.6

0.93

4.8

6.4

0.76

4.8

6.4

0.17

4.8

6.4

0.77

5.1

5.3

0.66

 

SD

(±3.2)

(±2.1)

 

(±2.9)

(±3.4)

 

(±2.9)

(±3.4)

 

(±2.9)

(±3.4)

 

(±3.2)

(±2)

 

T stage

pT1

20

4

0.005

28

2

0.004

29

2

0.003

19

0

0.028

22

5

0.42

pT2

12

0

7

1

11

0

8

0

12

0

pT3

9

5

13

5

13

6

7

3

12

5

pT4

0

2

0

2

0

1

1

0

0

1

pT1/2

32

4

0.02

35

3

0.02

40

2

0.004

27

0

0.02

34

5

0.084

pT3/4

9

7

13

7

13

7

8

3

12

6

Metastasis

N0M0

38

8

0.1

46

6

0.006

50

5

0.006

33

2

0.224

42

8

0.12

N + M+

3

3

2

4

3

4

2

1

4

3

Fuhrman Grade

G1/G2

16

4

1

18

2

0.47

20

2

0.47

14

1

1

18

3

0.73

G3/G4

25

7

30

8

33

7

21

2

28

8

Tumour necrosis

Present

10

3

1

14

3

1

16

1

0.42

10

0

0.55

14

3

1

Absent

29

7

33

6

35

7

23

3

30

7

Sarcomatoid change

Present

1

3

0.02

2

2

0.12

4

1

0.53

4

1

0.37

3

2

0.23

Absent

38

7

45

7

47

7

29

2

41

8

Microvascular invasion

Present

10

2

1

11

3

0.68

13

3

0.67

9

1

1

12

3

1

Absent

28

8

36

6

38

5

23

2

31

7

Renal Vein invasion

Present

6

2

1

8

2

0.67

8

2

0.62

3

1

0.32

7

2

1

Absent

31

8

37

7

41

6

28

2

34

8

Pelvicalyceal invasion

Present

4

0

0.56

6

1

1

6

1

1

2

1

0.25

7

0

0.32

Absent

33

10

39

8

43

7

29

2

34

10

Renal sinus invasion

Present

3

4

0.03

5

4

0.03

5

4

0.016

3

2

0.068

5

4

0.06

Absent

34

6

40

5

44

4

23

1

36

6

SSIGN score

0–2

17

5

0.16

21

3

0.26

22

2

0.29

16

1

0.011

17

4

0.43

S – Stage

03–Apr

4

0

7

0

6

1

4

0

4

0

SI – Size

05–Jun

11

1

9

2

11

2

3

1

10

3

G – Grade

07–Sep

4

2

6

2

8

1

8

0

8

1

N - Necrosis

≥10

1

2

2

2

2

2

0

1

2

2

  1. Numbers in columns under normal and LOH represent number of patients