Table 1 Baseline patient characteristics
Factor | Variable | No. of patients (%) |
|---|---|---|
| Â | Total number of patients | 1196 (100.0) |
Patient-related | Gender | Â |
|  |  Male | 885 (74.0) |
|  |  Female | 311 (26.0) |
| Â | Age (years) | Â |
|  |  <40 | 72 (6.0) |
|  |  40–65 | 772 (64.6) |
|  |  ≥ 65 | 352 (29.4) |
| Â | Body mass index (kg/m2) | Â |
|  |  <18.5 | 623 (52.1) |
|  |  18.5–20 | 93 (7.8) |
|  |  20–24 | 284 (23.7) |
|  |  ≥ 24 | 196 (16.4) |
| Â | Comorbidity | Â |
|  |  No | 1079 (90.2) |
|  |  Yes | 117 (9.8) |
| Â | Family history | Â |
|  |  No | 960 (80.3) |
|  |  Yes | 236 (19.7) |
| Â | Fibrinogen (g/L) | Â |
|  |  ≤ 4 | 887 (78.3) |
|  |  >4 | 246 (21.7) |
| Â | Carcinoembryonic antigen | Â |
|  |  <5 | 348 (77.9) |
|  |  ≥ 5 | 99 (22.1) |
| Â | Carbohydrate antigen 19-9 | |
|  |  <37 | 1103 (92.2) |
|  |  ≥ 37 | 93 (7.8) |
Tumor-related | Tumor location | Â |
|  |  Lower | 762 (63.8) |
|  |  Upper | 184 (15.4) |
|  |  Medium | 249 (20.8) |
| Â | Tumor size (cm) | Â |
|  |  <5 | 461 (38.6) |
|  |  ≥ 5 | 735 (61.4) |
| Â | Multi-organ involvement | Â |
|  |  No | 1141 (95.4) |
|  |  Yes | 55 (4.6) |
| Â | Multifocal | Â |
|  |  No | 1079 (97.6) |
|  |  Yes | 27 (2.4) |
| Â | Gross morphology | Â |
|  |  Flat | 142 (11.9) |
|  |  Uplift | 137 (11.4) |
|  |  Ulcerative | 146 (12.2) |
|  |  Infiltration ulcerative | 702 (58.7) |
|  |  Diffuse infiltration | 69 (5.8) |
| Â | T stage | Â |
|  |  1 | 195 (16.3) |
|  |  2 | 180 (15.1) |
|  |  3 | 395 (33.0) |
|  |  4 | 426 (35.6) |
| Â | N stage | Â |
|  |  N0 | 452 (37.8) |
|  |  N1 | 196 (16.4) |
|  |  N2 | 244 (20.4) |
|  |  N3 | 304 (25.4) |
| Â | Metastasis | Â |
|  |  No | 1121 (93.7) |
|  |  Yes | 75 (6.3) |
| Â | TNM | Â |
|  |  1 | 205 (17.1) |
|  |  2 | 318 (26.6) |
|  |  3 | 599 (50.1) |
|  |  4 | 74 (6.2) |
| Â | Differentiation | Â |
|  |  Poor | 513 (42.9) |
|  |  Medium | 246 (20.6) |
|  |  Signet ring | 34 (2.8) |
|  |  Mucus | 47 (3.9) |
|  |  Papillary | 8 (0.7) |
|  |  Mixed or other | 348 (29.1) |
Operation-related | Operation time (in min.) | Â |
|  |  ≤ 150 | 616 (51.5) |
|  |  >150 | 580 (48.5) |
| Â | Mode of lymph node dissection | |
|  |  Radical | 856 (71.6) |
|  |  Non-radical | 250 (20.9) |
|  |  Palliative | 90 (7.5) |
| Â | Cleared lymph node number | |
|  |  <15 | 667 (55.8) |
|  |  ≥ 15 | 529 (44.2) |
| Â | Intraoperative blood loss (ml) | |
|  |  ≤ 200 | 977 (81.7) |
|  |  >200 | 219 (18.3) |
| Â | Blood transfusion | Â |
|  |  No | 901 (75.3) |
|  |  Yes | 295 (24.7) |