CNOB Dose | Analyte | Cmax ± SE | AUC0-24 ± SE | Vss
| CL | t1/2
|
---|
mg/kg | | ng/mL | h*ng/mL | L/kg | L/h/kg | h |
---|
3.3 | CNOB | 141 ± 28.6 | 166 ± 23.5 | 81.5 | 17.7 | 4.6 |
| MCHB | 145 ± 30.4 | 148 ± 16.0 | 117 | 21.1 | 8.3 |
-
C
max
maximum observed concentration ± standard error (SE), AUC
0-24
area under the concentration curve from 0 to 24 h ± SE, V
ss
volume of distribution, CL clearance; t
1/2
terminal elimination half-life