Table 1 MCHB AUC in untransformed and HchrR6-transformed 4T1 tumors. AUC values in tumors were calculated over 24 h of CNOB treatment as determined by fluorescence imaging and LC/MS/MS. Statistical analysis of AUC was carried out by log transformed raw AUC data followed by two-tail paired t-test between each two groups of samples

From: Utilizing native fluorescence imaging, modeling and simulation to examine pharmacokinetics and therapeutic regimen of a novel anticancer prodrug