Fig. 2
Immunohistochemical analysis of EpEx in oral tissues. Paraffin-embedded sections of histologically normal mucosa, oral dysplasia and OSCC were stained using anti-EpEx monoclonal antibody as described in Methods section. Panel represents (a) normal oral mucosa showing no detectable EpExMem immunostaining; b Oral dysplasia showing intense EpExMem staining; c OSCC section illustrating reduced EpExMem in tumor cells; d OSCC section used as a negative control, showing no EpEx immunostaining in tumor cells where the primary antibody was replaced by isotype specific IgG (A-D original magnification x 200)