Table 8 Comparison of inflammatory markers and immunologic factors in two groups with neoadjuvant

IL-6 (ng/L)

 Before surgery

50.57 ± 21.45

51.42 ± 19.83

0.979

 POD1

119.54 ± 18.62

131.42 ± 21.58*

0.004

 POD3

138.42 ± 22.73

150.48 ± 21.97*

0.043

 POD7

112.52 ± 19.43

116.43 ± 22.57

0.573

CRP (mg/L)

 Before surgery

4.53 ± 1.24

4.45 ± 1.29

0.942

 POD1

61.32 ± 13.77

70.52 ± 11.56*

0.032

 POD3

132.73 ± 21.56

150.49 ± 25.72*

0.013

 POD7

49.78 ± 15.84

60.43 ± 16.38*

0.035

Globulin (g/l)

 Before surgery

25.67 ± 3.34

25.82 ± 4.39

1.000

 POD1

21.43 ± 3.63

20.21 ± 3.45

0.760

 POD3

24.76 ± 3.82

21.64 ± 2.94*

0.023

 POD7

25.73 ± 3.35

25.87 ± 4.09

0.848

IgG (g/l)

 Before surgery

13.76 ± 3.13

13.62 ± 3.42

0.858

 POD1

7.42 ± 1.42

5.23 ± 1.35*

0.031

 POD3

9.42 ± 3.53

6.44 ± 2.95*

0.001

 POD7

12.56 ± 2.67

11.94 ± 3.83

0.656

IgA (g/l)

 Before surgery

2.19 ± 0.29

2.21 ± 0.25

0.769

 POD1

1.61 ± 0.37

1.34 ± 0.25*

0.017

 POD3

1.85 ± 0.42

1.51 ± 0.51*

0.004

 POD7

2.04 ± 0.37

2.15 ± 0.42

0.753

IgM (g/l)

 Before surgery

1.14 ± 0.31

1.11 ± 0.41

0.893

 POD1

0.71 ± 0.39

0.72 ± 0.33

0.957

 POD3

0.67 ± 0.22

0.64 ± 0.32

0.873

 POD7

1.09 ± 0.43

1.10 ± 0.42

0.673

CD3+

 Before surgery

55.62 ± 2.43

56.82 ± 2.58

0.875

 POD1

46.73 ± 2.52

44.09 ± 2.03*

0.043

 POD3

49.82 ± 2.43

46.17 ± 2.35*

0.033

 POD7

53.85 ± 2.05

54.04 ± 2.73

0.482

CD4+

 Before surgery

42.43 ± 3.57

42.48 ± 4.92

0.803

 POD1

32.52 ± 4.13

29.12 ± 5.02*

0.025

 POD3

35.32 ± 3.90

32.55 ± 5.02*

0.013

 POD7

41.42 ± 5.24

40.98 ± 4.27

0.484

CD4+/CD8+

 Before surgery

1.52 ± 0.41

1.55 ± 0.45

0.842

 POD1

1.33 ± 0.36

1.11 ± 0.41*

0.027

 POD3

1.47 ± 0.56

1.32 ± 0.37*

0.025

 POD7

1.50 ± 0.36

1.52 ± 0.29

0.562