Table 7 Comparison of inflammatory markers and immunologic factors in two groups without neoadjuvant

IL-6 (ng/L)

 Before surgery

52.13 ± 25.54

54.67 ± 22.36

0.651

 POD1

123.43 ± 20.73

139.26 ± 22.92*

0.007

 POD3

144.05 ± 26.39

156.25 ± 25.38*

0.032

 POD7

117.23 ± 21.29

123.36 ± 25.56

0.321

CRP (mg/L)

 Before surgery

4.92 ± 1.53

4.83 ± 1.72

0.953

 POD1

66.37 ± 12.93

75.52 ± 14.88*

0.023

 POD3

138.84 ± 22.04

156.58 ± 29.21*

0.019

 POD7

53.84 ± 16.95

64.06 ± 16.74*

0.031

Globulin (g/l)

 Before surgery

28.82 ± 3.93

27.97 ± 5.21

0.643

 POD1

22.25 ± 3.83

21.09 ± 3.90

0.231

 POD3

25.72 ± 3.08

22.68 ± 2.89*

0.026

 POD7

28.56 ± 2.25

27.74 ± 4.04

0.447

IgG (g/l)

 Before surgery

15.82 ± 2.98

14.18 ± 3.69

0.585

 POD1

8.87 ± 1.65

6.32 ± 1.19*

0.025

 POD3

10.88 ± 3.37

7.94 ± 2.87*

0.000

 POD7

14.51 ± 2.83

13.97 ± 3.63

0.231

IgA (g/l)

 Before surgery

2.76 ± 0.33

2.85 ± 0.27

0.654

 POD1

1.71 ± 0.54

1.45 ± 0.14*

0.013

 POD3

1.98 ± 0.47

1.67 ± 0.52*

0.002

 POD7

2.53 ± 0.33

2.42 ± 0.38

0.585

IgM (g/l)

 Before surgery

1.24 ± 0.33

1.19 ± 0.46

0.841

 POD1

0.85 ± 0.49

0.81 ± 0.32

0.432

 POD3

0.77 ± 0.17

0.71 ± 0.26

0.233

 POD7

1.15 ± 0.53

1.21 ± 0.50

0.190

CD3+

 Before surgery

57.92 ± 2.63

58.23 ± 2.48

0.764

 POD1

48.87 ± 2.51

46.13 ± 2.78*

0.047

 POD3

51.17 ± 2.20

48.19 ± 2.31*

0.013

 POD7

55.59 ± 2.28

53.07 ± 2.84

0.230

CD4+

 Before surgery

44.28 ± 3.48

44.73 ± 4.52

0.864

 POD1

34.95 ± 4.72

31.07 ± 5.09*

0.020

 POD3

38.52 ± 3.61

34.54 ± 5.22*

0.016

 POD7

43.38 ± 5.86

42.48 ± 3.84

0.382

CD4+/CD8+

 Before surgery

1.64 ± 0.32

1.55 ± 0.49

0.872

 POD1

1.43 ± 0.21

1.20 ± 0.51*

0.036

 POD3

1.54 ± 0.55

1.41 ± 0.34*

0.018

 POD7

1.57 ± 0.24

1.51 ± 0.28

0.341