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Table 7 Comparison of inflammatory markers and immunologic factors in two groups without neoadjuvant

From: Fast-track surgery improves postoperative clinical recovery and cellular and humoral immunity after esophagectomy for esophageal cancer

Factor and time FTS group (n = 60) Conventional group (n = 62) P value
IL-6 (ng/L)    
 Before surgery 52.13 ± 25.54 54.67 ± 22.36 0.651
 POD1 123.43 ± 20.73 139.26 ± 22.92* 0.007
 POD3 144.05 ± 26.39 156.25 ± 25.38* 0.032
 POD7 117.23 ± 21.29 123.36 ± 25.56 0.321
CRP (mg/L)    
 Before surgery 4.92 ± 1.53 4.83 ± 1.72 0.953
 POD1 66.37 ± 12.93 75.52 ± 14.88* 0.023
 POD3 138.84 ± 22.04 156.58 ± 29.21* 0.019
 POD7 53.84 ± 16.95 64.06 ± 16.74* 0.031
Globulin (g/l)    
 Before surgery 28.82 ± 3.93 27.97 ± 5.21 0.643
 POD1 22.25 ± 3.83 21.09 ± 3.90 0.231
 POD3 25.72 ± 3.08 22.68 ± 2.89* 0.026
 POD7 28.56 ± 2.25 27.74 ± 4.04 0.447
IgG (g/l)    
 Before surgery 15.82 ± 2.98 14.18 ± 3.69 0.585
 POD1 8.87 ± 1.65 6.32 ± 1.19* 0.025
 POD3 10.88 ± 3.37 7.94 ± 2.87* 0.000
 POD7 14.51 ± 2.83 13.97 ± 3.63 0.231
IgA (g/l)    
 Before surgery 2.76 ± 0.33 2.85 ± 0.27 0.654
 POD1 1.71 ± 0.54 1.45 ± 0.14* 0.013
 POD3 1.98 ± 0.47 1.67 ± 0.52* 0.002
 POD7 2.53 ± 0.33 2.42 ± 0.38 0.585
IgM (g/l)    
 Before surgery 1.24 ± 0.33 1.19 ± 0.46 0.841
 POD1 0.85 ± 0.49 0.81 ± 0.32 0.432
 POD3 0.77 ± 0.17 0.71 ± 0.26 0.233
 POD7 1.15 ± 0.53 1.21 ± 0.50 0.190
CD3+    
 Before surgery 57.92 ± 2.63 58.23 ± 2.48 0.764
 POD1 48.87 ± 2.51 46.13 ± 2.78* 0.047
 POD3 51.17 ± 2.20 48.19 ± 2.31* 0.013
 POD7 55.59 ± 2.28 53.07 ± 2.84 0.230
CD4+    
 Before surgery 44.28 ± 3.48 44.73 ± 4.52 0.864
 POD1 34.95 ± 4.72 31.07 ± 5.09* 0.020
 POD3 38.52 ± 3.61 34.54 ± 5.22* 0.016
 POD7 43.38 ± 5.86 42.48 ± 3.84 0.382
CD4+/CD8+    
 Before surgery 1.64 ± 0.32 1.55 ± 0.49 0.872
 POD1 1.43 ± 0.21 1.20 ± 0.51* 0.036
 POD3 1.54 ± 0.55 1.41 ± 0.34* 0.018
 POD7 1.57 ± 0.24 1.51 ± 0.28 0.341
  1. Variables were expressed as the median ± quartile
  2. * P <0.05