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Table 10 Comparison of inflammatory markers and immunologic factors in two groups with MIE

From: Fast-track surgery improves postoperative clinical recovery and cellular and humoral immunity after esophagectomy for esophageal cancer

Factor and time

FTS group (n = 65)

Conventional group (n = 67)

P value

IL-6 (ng/L)

   

 Before surgery

52.33 ± 24.37

53.42 ± 22.73

0.764

 POD1

119.34 ± 21.57

134.42 ± 22.53*

0.005

 POD3

140.05 ± 25.63

151.67 ± 24.52*

0.035

 POD7

113.72 ± 22.42

117.66 ± 25.74

0.152

CRP (mg/L)

   

 Before surgery

4.62 ± 1.63

4.53 ± 1.57

0.842

 POD1

62.42 ± 13.83

71.42 ± 14.32*

0.027

 POD3

134.73 ± 22.57

153.82 ± 25.62*

0.017

 POD7

50.46 ± 15.73

61.43 ± 15.66*

0.012

Globulin (g/l)

   

 Before surgery

27.72 ± 3.55

27.58 ± 5.14

0.942

 POD1

23.57 ± 3.73

22.64 ± 3.73

0.543

 POD3

25.42 ± 3.95

23.31 ± 3.52*

0.021

 POD7

28.04 ± 2.76

27.87 ± 4.13

0.735

IgG (g/l)

   

 Before surgery

14.63 ± 2.57

14.03 ± 3.1

0.872

 POD1

9.43 ± 1.25

7.62 ± 1.17*

0.028

 POD3

11.82 ± 3.52

8.73 ± 2.94*

0.002

 POD7

14.42 ± 2.76

13.52 ± 3.33

0.542

IgA (g/l)

   

 Before surgery

2.57 ± 0.31

2.77 ± 0.29

0.767

 POD1

1.83 ± 0.41

1.54 ± 0.22*

0.015

 POD3

1.99 ± 0.35

1.69 ± 0.42*

0.000

 POD7

2.55 ± 0.32

2.52 ± 0.32

0.652

IgM (g/l)

   

 Before surgery

1.28 ± 0.31

1.21 ± 0.36

0.853

 POD1

0.94 ± 0.43

0.92 ± 0.35

0.482

 POD3

0.87 ± 0.21

0.81 ± 0.32

0.353

 POD7

1.25 ± 0.46

1.22 ± 0.52

0.320

CD3+

   

 Before surgery

57.43 ± 2.82

58.12 ± 2.73

0.873

 POD1

49.69 ± 2.43

47.02 ± 2.57*

0.044

 POD3

53.38 ± 2.57

49.93 ± 2.65*

0.017

 POD7

56.73 ± 2.52

56.48 ± 2.49

1.000

CD4+

   

 Before surgery

44.52 ± 3.46

44.37 ± 4.41

1.000

 POD1

35.87 ± 4.15

32.35 ± 4.89*

0.022

 POD3

39.98 ± 3.73

35.43 ± 4.64*

0.013

 POD7

44.73 ± 5.02

43.76 ± 3.92

0.859

CD4+/CD8+

   

 Before surgery

1.58 ± 0.30

1.52 ± 0.42

0.973

 POD1

1.49 ± 0.24

1.26 ± 0.43*

0.031

 POD3

1.64 ± 0.45

1.45 ± 0.28*

0.015

 POD7

1.56 ± 0.32

1.50 ± 0.37

0.458

  1. Variables were expressed as the median ± quartile
  2. *P <0.05